I'm currently running a Toshiba Qosmio X775-Q7272 with an nVidia GeForce GTX 560M graphics card. I've been having a lot of problems with it (random blue screens of death, Mass Effect 2 crashes every time I try to go the menu). So I tried to download the latest driver on Toshiba's site (bad idea, I know), that didn't work (it actually made my computer freeze after about a minute after start up). So I tried downloading the latest beta driver, and that has actually run, though it still gives me the blue screen of death whenever I try to load up the nvidia settings in the control panel or on the taskbar. So I'm going to download and install the latest WHQL driver now and see if that works better.
EDIT: Ok, scratch that. The latest WHQL driver works horribly. It gets just pasted the "Starting Windows" screen and then it just goes black. I had to start up in safe mode and uninstall the driver in order to get back on my laptop. So looks like back to the latest beta for the time being. I'm going to try it on a high-graphics game to see if it still acts up.